It may be a cliche, but you get exactly what you pay for. There are many cheap brands that uses synthetic alternative extracted from the tobacco leaf. Avoid buying these. You should buy the best quality CoQ10 where the package clearly says that ingredients are manufactured by 100% fermentation process. There are several decent brands in the market. Read below on some of them. You will be paying higher retail prices for high potency and best quality CoQ10. The best Coq10 is the one with the right potent (read not higher than what we need), which ensures higher bio availability, and from reputed manufacturers. Avoid buying Ubiquinone since, unlike Ubiquinol, it will not get absorbed and will be a waste. Japanese labs are leaders in CoQ10 Ubiquinol research who established the supremacy of absorption capabilities of Ubiquinol form of CoQ10. No wonder they dominate the pharmaceutical grade CoQ10 in the market.

Most reputed manufactures get their ingredients from Japan and formulate the capsules here in US. (Mix olive or other oil with CoQ10 ingredient and produce soft gels). Among the top Ubiquinol ingredient manufacturer from Japan is Kaneka Corporation of Osaka, Japan the world’s largest manufacturer of CoQ10. Kaneka Q10™ is offers 100% pure, naturally fermented from a yeast (trans-isomer) ingredient. The raw material is pharmaceutical grade and non-GMO. Kaneka has been manufacturing CoQ10 in Japan since 1977 and has recently opened a state of the art CoQ10 manufacturing plant in the kanekaq10USA, located in Pasadena, Texas. Sp if you want to buy the best CoQ10 looks for the the word Kaneka in the bottle.


Another best Coq10 brand you can buy is Q-Gel. Tishcon Corp’s Q-Gel® CoQ10 is a 100% Hydrosoulable CoQ10 which is also Liposoluble (Duosoluble™).  Q-gel is available in the form of power that you cam mix with oil as well as soft gel and liquid. Q-Gel site says that the products manufactured via the Biosolv® process were studied in patients with hypertension. Results of these studies proved conclusively the direct effect of the enhanced bioavailibility of Q-Gel®. Expect to pay a higher retail price compared to cheaper brands

Douglas lab

Douglas lab is a among the highly regarded supplement manufacturers in USA and is known for their pharmaceutical quality, prescription grade supplements. The retail price of the supplements are high, but well worth it as it among the best CoQ10 brands. Citrus Solu-Q™, provided by Douglas Laboratories® is a Caplique™ containing natural coenzyme Q10 soft gel in a patented, naturally self-assembling nano-colloid system for enhanced absorption. In a clinical study in humans, supplementation with CoQ10 utilizing the patented VESIsorb® technology resulted in greater absorption compared with other CoQ10 products. Citrus Solu-Q™ is unique among coenzyme Q10 products as it utilizes the patented VESIsorb® technology to deliver coenzyme Q10. When mixed with an aqueous system, this patented technology results in the formation of a nanocolloid containing solubilized CoQ10. This association colloid delivery system contains a highly uniform distribution of droplets that are less than 100 nm in diameter. The size and structure of these droplets allow for enhanced solubility and absorption of coenzyme

Life Extension

Another decent supplement manufacturer is Life extension which offer best quality CoQ10 formulation containing an organic compound called PrimaVie® shilajit that research shows doubles levels of CoQ10 in the mitochondria. Life Extnesion’s Super Ubiquinol CoQ10 soft gel with Enhanced Mitochondrial Support™ combines super absorbable ubiquinol CoQ10 with shilajit to generate a powerful synergy that supports more youthful cellular energy production than CoQ10 alone. Life extension claims that Shilajit has been shown to help restore and sustain cellular energy. Their latest studies reveal that when shilajit is combined with CoQ10, cellular energy gains substantially increase. In a preliminary study, the combination of CoQ10 and shilajit produced a 56% increase in cellular energy production in the brain — 40% better than CoQ10 alone. In muscle there was a 144% increase, or 27% better than CoQ10 alone. Life extension CoQ10 prices are not as high as Douglas lab. If you are a member of life Extension, you can get a discount on their retail price.


Now offers NOW® CoQ10soft gel in Pharmaceutical Grade (USP). NOW sells only the natural, 100% all-trans form of CoQ10 soft gel that is produced using natural fermentation and purchased from the leading Japanese suppliers. This is considered to be the best and most natural form available. Now website says that Differences in absorption or utilization of CoQ10 products are mostly associated with oils added to powdered CoQ10 within a softgel capsule. These differences are far less important when the supplement is taken at the same time as other oils or oil-based supplements in the diet, rather than between meals. This makes it possible to take CoQ10 in a vegetarian form – or even as a powder – and still enjoy the benefits of enhanced absorption. The retail price of Now brand is considerably cheaper as they are more voulme


The name is misleading. This is NOT “Ubiquinol” which is the type you should buy. What Costco sells is just plain CoQ10 with vitamin E.  However Qunol™ seems to have some good reviews from users and it is kind of close to the Ubiquinol form. Give it a try if you need and see the results. I would not buy this in bulk. Also don’t look at Costco as a cheap generic store brand. It is no secret that Costco has one of the best purchasing divisions in the world and they are sourcing this from Quten Research Institute based in Novato, California with the brand name called Qunol. Coscto website claims that 7 separate peer-reviewed and published clinical studies have shown the new patented technology in Qunol™ soft gel gives it the highest absorption of all CoQ10 supplements tested – up to 300% greater than competing brands and it is the gold standard. The difference is in Qunol’s advanced solubility. Qunol is the original CoQ10 supplement that is proven to be both 100% Lipid and Hydro soluble. Most competing brands are Lipid soluble only, which limits their absorption. Qunol provides complete solubility that gives you best absorption. Qunol is made with the highest quality all-natural Coenzyme Q10, not synthetic like many competing brands. This guarantees best absorption and highest bio-availability.


The above statements have not been evaluated by the FDA. This products are not intended to diagnose, treat, cure or prevent any disease.